GMC Sierra 2500 Key Replacement Guide

Last updated: August 2026 · Verified OEM part numbers

Quick answer: The GMC Sierra 2500 (2021-2023) uses the HYQ1ES 13533423 433MHz 46 Chip 3+1 Button (Start) Smart Key for GMC Sierra Terrain (SKU PCK-GC-2014-P) — verified against OEM part numbers. See the full compatibility table below.

Compatible keys for GMC Sierra 2500

Before you order

• Match the year range — GMC changed key systems across model years. Check your registration year.
• Check your current key — the OEM number printed on your key matches the table above.
• Programming — smart keys need a compatible programmer (Xhorse, VVDI, Autel). We can advise which one works for each key.

Frequently asked questions

Which key fits my GMC Sierra 2500?

The GMC Sierra 2500 (2021-2023) uses the HYQ1ES 13533423 433MHz 46 Chip 3+1 Button (Start) Smart Key for GMC Sierra Terrain (SKU PCK-GC-2014-P). Check the table above for all compatible options, verified against OEM part numbers.

Do you supply GMC Sierra 2500 keys wholesale?

Yes. We supply locksmiths and key distributors at wholesale prices with MOQ from 5 units. Message us on WhatsApp for today's price list.

Can a GMC Sierra 2500 key be programmed without the dealer?

In most cases yes, using tools like Xhorse, VVDI or Autel. We can advise the right programmer for each key SKU.

Related: All GMC keys · All guides · Key Finder

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